In the last decade there has been an explosion of interest in viral
therapies for cancer. Viral agents have been developed that are
harmless to normal tissues but selectively able to kill cancer
cells. These agents have been endowed with additional selectivity
and potency through genetic manipulation. Increasingly these
viruses are undergoing evaluation in clinical trials, both as
single agents and in combination with standard chemotherapy and
radiotherapy.
This book provides a comprehensive yet succinct overview of the
current status of viral therapy of cancer. Chapters coherently
present the advances made with individual agents and review the
biological and clinical background to a range of viral therapies:
structured to proceed from basic science at the bench to the
patient's bedside, they give an up-to-date and realistic evaluation
of a therapy's potential utility for the cancer patient. Presents
state-of-the-art knowledge on how viruses can be, and have been,
used in novel therapeutic approaches for the treatment of cancer
Describes the use of viruses as oncolytic agents, killing cells
directly Editors are experts in the field, with experience of both
laboratory and clinical research
Viral Therapy of Cancer is essential reading for both basic
scientists and clinicians with an interest in viral therapy and
gene therapy.
General
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