Reflecting the major advances that have been made in the field over
the past decade, this book provides an overview of current models
of biological systems. The focus is on simple quantitative models,
highlighting their role in enhancing our understanding of the
strategies of gene regulation and dynamics of information transfer
along signalling pathways, as well as in unravelling the interplay
between function and evolution. The chapters are self-contained,
each describing key methods for studying the quantitative aspects
of life through the use of physical models. They focus, in
particular, on connecting the dynamics of proteins and DNA with
strategic decisions on the larger scale of a living cell, using E.
coli and phage lambda as key examples. Encompassing fields such as
quantitative molecular biology, systems biology and biophysics,
this book will be a valuable tool for students from both biological
and physical science backgrounds.
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