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Medaka - A Model for Organogenesis, Human Disease, and Evolution (Paperback, 2011 ed.)
Loot Price: R5,461
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Medaka - A Model for Organogenesis, Human Disease, and Evolution (Paperback, 2011 ed.)
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Oryzias latipes, known as medaka, is a model organism from East
Asia. Breeding of this small, egg-laying freshwater teleost fish
has long been popular among hobbyists in Japan. Now, as biological
science has entered the genome era, the medaka provides significant
advantages that make it one of the most valuable vertebrate models:
a large collection of spontaneous mutants collected over a century,
the presence of highly polymorphic inbred lines established over
decades, and a recently completed genome sequence. This book is the
first comprehensive monograph to cover a variety of medaka
research. It opens with a historical view of medaka, followed by a
series of research topics in the four major areas where the medaka
is increasingly important: genomics, genetics, and resources;
organogenesis and disease models; germ cells, sex determination,
and reproduction; and evolution. Readers will find state-of-the-art
information on medaka genetics and genomics such as the first
isolation of active transposons in vertebrates, the influence of
chromatin structure on sequence variation, fine QTL analysis, and
versatile mutants as human disease models.
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