Protein kinases play a critical role in cellular processes that
impact overall organismal health and function. Of the kinases that
collectively make up the Human Kinome, CK2 has garnered special
attention because of its significant role in the generation of the
human phosphoproteome. The role CK2 plays in the development of
cancer and other disease has also made it of significant interest
for its potential role in future therapeutics. "Protein Kinase CK2"
comprehensively brings together the varied work being done on this
critical enzyme.
"Protein Kinase CK2" is logically divided into three sections.
The first section reviews key molecular and structural aspects of
the enzyme. The second section looks at functional aspects of CK2
and the diverse roles it plays in cellular development, function,
and health. The final section focuses on CK2 and cancer, looking at
the impacts of the kinase on neoplastic development and its rapidly
developing role as a therapeutic agent.
With contributions from the world's leading experts in the
field, "Protein Kinase CK2" will serve as an invaluable guide to
the expanding and vibrant body of research being performed on this
enzyme. This will be an essential volume for anyone working in the
fields of biochemistry, protein science, signal transduction,
metabolic regulation, and cancer biology and therapeutics.
EditorLorenzo A. Pinna is Professor in the Department of
Biomedical Sciences at the University of Padua, Padua, Italy.
Also Published in the Wiley-IUBMB Series on Biochemistry and
Molecular Biology:
"Plant Phenolics and Human Health: Biochemistry, Nutrition, and
Pharmacology"Edited by Cesar G. FragaISBN: 978-0-470-28721-7
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