The focus of this report is upon information essential to the
understanding of the toxic action of cadmium and the relationship
between dose (exposure) and effects on human beings and animals.
The therapy of cadmium poisoning has not been discussed.This review
on cadmium in the environment has been performed under a contract
between the U.S. Environmental Protection Agency and the Department
of Environmental Hygiene of the Karolinska Institute, Sweden. The
report is intended to serve as a background paper for a future Air
Quality Criteria document on cadmium. Therefore, particular
attention has been given to information relevant for the evaluation
of risks due to long-term exposure to low concentrations of
cadmium. Acute effects from short-term exposure to high
concentrations are dealt with briefly. In vitro studies without
bearing on the main problem have not been dealt with.The report is
not limited to effects from exposure via inhalation. Newly
accessible information, showing that large populations may be
exposed considerably via the oral route, can elucidate chronic
effects of cadmium in general. Man and animals can be victims of
secondary exposure through vehicles such as food and water which
have been contaminated by cadmium in air.
General
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