The skin is the largest human organ system. Loss of skin
integrity due to injury or illness results in a substantial
physiologic imbalance and ultimately in severe disability or death.
The most common cause of significant skin loss is thermal injury,
followed by trauma and chronic ulcerations.
Over the past decades extraordinary advances have been made in
the understanding of cellular and molecular processes of wound
healing and the pathobiology of chronic wounds. This knowledge has
led to wound care innovations that facilitate more rapid closure of
wounds with better functional and aesthetic outcome. A sensible and
resource-saving utilization of these innovative technologies
requires a broad knowledge of these processes and innovations.
This book intends to give an overview about today's wound care
developments in tissue engineering and skin replacement. It
presents a variety of indications and diversities of clinical
applications to help the surgeon select a specific procedure for
each clinical situation.
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