DNA Repair in Cancer Therapy (Hardcover, 2004 ed.)

A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Cancer Drug Discovery and Development
Release date:	March 2004
First published:	2004
Editors:	Lawrence C. Panasci • Moulay A. Alaoui-Jamali
Dimensions:	235 x 155 x 22mm (L x W x T)
Format:	Hardcover
Pages:	363
Edition:	2004 ed.
ISBN-13:	978-1-58829-298-8
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-58829-298-3
Barcode:	9781588292988

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