How does dietary restriction affect the physiological and
biochemical state of laboratory animals? How will the present
conclusions affect further research? What are the implications for
human health and safety assessment? These are the main questions
asked in this book by leading international researchers. After a
first look at feeding regimens and diets of laboratory animals, the
book elaborates on a variety of age-associated toxicological and
pathological endpoints including tumor development. The following
sections detail the underlying mechanisms which may induce the
broad spectrum of physiological and biochemical changes. This
summary of current multidisciplinary research will enhance
understanding of the practical applications and implications of
dietary restriction.
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