Retinoic acid (RA) is a signalling molecule involved in many
important pathways in every cell. When RA binds to RA receptors and
activates them, cell cycle arrest, differentiation and apoptosis
can occur. In this book, the authors present topical research in
the study of the structure, mechanisms and roles in disease of
retinoic acid. Topics discussed include retinoid signalling in
mammalian inner ear development; nuclear receptors for retinoids
involved in the control of expression activity of p-glycoprotein;
retinoic acid signaling and immunotherapy of cancer; using retinoic
acid in molecular medicine and retinol/vitamin A signalling and
self-renewal of stem cells.
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