This book presents a framework for development, optimization, and
evaluation of behavioral, biobehavioral, and biomedical
interventions. Behavioral, biobehavioral, and biomedical
interventions are programs with the objective of improving and
maintaining human health and well-being, broadly defined, in
individuals, families, schools, organizations, or communities.
These interventions may be aimed at, for example, preventing or
treating disease, promoting physical and mental health, preventing
violence, or improving academic achievement. This volume introduces
the multiphase optimization strategy (MOST), pioneered at The
Methodology Center at the Pennsylvania State University, as an
alternative to the classical approach of relying solely on the
randomized controlled trial (RCT). MOST borrows heavily from
perspectives taken and approaches used in engineering, and also
integrates concepts from statistics and behavioral science,
including the RCT. As described in detail in this book, MOST
consists of three phases: preparation, in which the conceptual
model underlying the intervention is articulated; optimization, in
which experimentation is used to gather the information necessary
to identify the optimized intervention; and evaluation, in which
the optimized intervention is evaluated in a standard RCT. Through
numerous examples, the book demonstrates that MOST can be used to
develop interventions that are more effective, efficient,
economical, and scalable. Optimization of Behavioral,
Biobehavioral, and Biomedical Interventions: The Multiphase
Optimization Strategy is the first book to present a comprehensive
introduction to MOST. It will be an essential resource for
behavioral, biobehavioral, and biomedical scientists;
statisticians, biostatisticians, and analysts working in
epidemiology and public health; and graduate-level courses in
development and evaluation of interventions.
General
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