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Ras Signaling - Methods and Protocols (Hardcover, 2014 ed.)
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Ras Signaling - Methods and Protocols (Hardcover, 2014 ed.)
Series: Methods in Molecular Biology, 1120
Expected to ship within 12 - 17 working days
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Featuring experimental approaches that shed light on the complexity
of Ras GTPase biological functions, Ras Signaling: Methods and
Protocols contains general overviews and detailed applications of
both well-established and recently developed research techniques,
including biochemical, biophysical, molecular biology, genetic and
behavioral approaches, advanced high resolution fluorescence and
electron microscopy imaging and "omics" technologies. Through this,
the detailed volume provides information on expression,
post-translational modifications, subcellular localization and
dynamics, regulatory mechanisms of upstream and downstream
signaling pathways and ultimately, biological activities and
functions of Ras GTPases in different model systems, including high
and low eukaryotic organisms. Written in the highly successful
Methods in Molecular Biology series format, chapters include brief
introductions, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols and tips on
troubleshooting and avoiding known pitfalls. Wide-ranging and
authoritative, Ras Signaling: Methods and Protocols serves as an
aid for investigators of different backgrounds and interests
related to the multiple physiological and pathological functions of
the large superfamily of Ras GTPases.
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