Books > Science & Mathematics > Biology, life sciences > Cellular biology
|
Buy Now
Regulation of Gene Expression in Animal Viruses (Paperback, Softcover reprint of the original 1st ed. 1993)
Loot Price: R1,584
Discovery Miles 15 840
|
|
Regulation of Gene Expression in Animal Viruses (Paperback, Softcover reprint of the original 1st ed. 1993)
Series: NATO Science Series A:, 240
Expected to ship within 10 - 15 working days
|
Viruses, being obligatory parasites of their host cells, rely on a
vast supply of cellular components for their replication,
regardless of whether infection leads to cell death or to the state
of persistence. Animal viruses are providing scientists with
relatively simple models to study the molecular biology of genome
replication and gene expression. Whereas viruses use, in general,
pathways of macromolecular biosynthesis common to the host cell,
they have a cunning ability to adopt unusual mechanisms of gene
expression and gene replication, provided these special pathways
offer an advantage in competition for cellular resources. Any study
of viral gene expression and replication is likely to lead also to
new insights in cellular metabolism. The discoveries of cis-acting
regulatory elements in transcription, the phenomenon of splicing of
pre mRNA, and cap-dependent and cap-independent initiation of
translation may be cited as examples. In addition, animal virus
genomes contain elements and encode proteins that are very useful
for the design of vectors for gene cloning and expression in
mammalian cells. Apart from the basic interest in their biology,
viruses have gained notoriety, of course, because they are
pathogens. Human animal viruses may cause diseases ranging from the
deadly (AIDS) to the benign (common cold). All studies on animal
viruses potentially lead to the development of tools for their
control, be it through prevention by immunization or treatment with
antiviral drugs. Finally, viruses have yielded invaluable reagents
in molecular biology as, for example, the vaccinia virus vector for
the expression of foreign genes.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.