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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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AIDS-Related Neoplasias (Paperback, Softcover reprint of the original 1st ed. 1988)
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AIDS-Related Neoplasias (Paperback, Softcover reprint of the original 1st ed. 1988)
Series: Recent Results in Cancer Research, 112
Expected to ship within 10 - 15 working days
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The acquired immunodeficiency syndrome (AIDS) and the AIDS- related
complex (ARC) are caused by the human immunodeficien- cy virus
(HIV-I), previously known as human T-celllymphotropic virus type
III (HTLV-III) or lymphadenopathy-associated virus (LA V). It seems
that additional retroviruses (HIV-II and perhaps 1 3 others) are
able to cause variants of AIDS or ARC. - Patients infected wi~h the
virus may (but do not necessarily) de- velop a wide range of
clinical symptoms that are not directly relat- ed to the virus
itself, but are secondary to the devastating effects of the viral
infection on' the human immune system. The virus thus renders the
patient susceptible to a variety of opportunistic infec- tions with
other viruses (such as cytomegalovirus), bacteria, fungi, and
protozoa, as well as to the development of simultaneous or
subsequent malignant tumors. The new topic of AIDS and cancer is a
challenging and frighten- ing aspect of present-day medicine and
health politics. With the growing prevalence of the human
immunodeficiency virus(es) and clinical correlates ranging from
persistent generalized lymphaden- opathy (PGL) to full-blown AIDS
in our population, we will also encounter a steadily rising number
of patients with both AIDS and neoplasias, such as Kaposi's
sarcoma, Hodgkin's and non-Hodg- kin's lymphomas, anal cancer, and
a variety of additional malig- 4 nant tumors. , 5 1 Gallo RC,
Salahuddin SZ, Popvic M et a!. (1984) Frequent detection and
isolation of cytopathic retroviruses (HTL V-III) from patients with
AIDS and at risk for AIDS. Science 224: 500-503.
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