This monograph has dealt comprehensively with the genetic and
molecular aspects of breast cancer. Introductory chapter highlights
certain aspects like epidemiology and demographic trends in various
regions of the world. The mechanism of involvement of different
genes in the etiological process is discussed.Present day
literature dealing with this subject has been reviewed and the
referrences are provided at the end of the book. The book lays main
focus on BRCA protein expression and its derangement in sporadic
breast cancer and whether this premise can be utilized in improving
on the treatment regimen selection for the patients.This provides a
new insight into the subject in the sense that so far this aspect
has not been thoroughly studied.The treatment regimen selection has
hitherto been dictated by hormonal receptor and Her2/neu receptor
analysis.A new hypothetical model of managing breast cancer in
sporadic setting has been provided in the present book based on the
expression of BRCA protein rather than on the basis of mutational
analysis.
General
Imprint: |
Lap Lambert Academic Publishing
|
Country of origin: |
Germany |
Release date: |
May 2012 |
First published: |
May 2012 |
Authors: |
M Ashraf
|
Dimensions: |
229 x 152 x 6mm (L x W x T) |
Format: |
Paperback - Trade
|
Pages: |
96 |
ISBN-13: |
978-3-659-11693-3 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
General
|
LSN: |
3-659-11693-9 |
Barcode: |
9783659116933 |
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