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Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis (Paperback, Softcover reprint of the original 1st ed. 1999)
Loot Price: R1,441
Discovery Miles 14 410
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Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis (Paperback, Softcover reprint of the original 1st ed. 1999)
Series: Topics in Neuroscience
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We have entered an exciting period in the study of multiple
sclerosis and its treatment. Central to this progress has been the
introduction of magnetic reso nance techniques. When Young and his
colleagues published the first images of the brain in multiple
sclerosis at the end of 1981, it was at once obvious that magnetic
resonance imaging would playa major role in diagnosis. Intuitively
one felt that it would also have a role in increasing our
understanding of the pathogenesis of the disease and in monitoring
treatment. And so it has proved. Important problems however remain,
perhaps the most important of which at present is the weak
predictive power of standard magnetic resonance ima ging methods in
determining the possibility of progression of impairment and
disability. Recently, there have been advances which promise to
overcome some of these problems, but decisions about what approach
to adopt in selecting patients for clinical trials and which
techniques to use in monitoring treatment during their course are
still difficult. In this book, Dr. Filippi and his colleagues have
assembled an outstanding group of contributors whose work is
central to the progress that is being made. The coverage of the
issues involved in the use of magnetic resonance techniques in
assessing therapeutic effect is comprehensive and, though the field
is chan ging rapidly, the principles and much of the detail in the
book are likely to have lasting value."
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