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Metabotropic Glutamate Receptors - Molecular Mechanisms, Role in Neurological Disorders & Pharmacological Effects (Hardcover)
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Metabotropic Glutamate Receptors - Molecular Mechanisms, Role in Neurological Disorders & Pharmacological Effects (Hardcover)
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As the most abundant excitatory neurotransmitter in the brain,
glutamate plays an important role in numerous aspects of normal and
pathological brain function. This book provides an overview of the
role of metabotropic glutamate receptors (mGluRs) in basic brain
functioning, such as autonomic regulation, synaptic plasticity, and
learning and memory. Also provided are up-to-date summaries of
recent progress towards identifying how mGluRs both mediate and
represent novel pharmacotherapeutic targets for the treatment of
various neurological and neuropsychiatric disorders, such as
depression, anxiety, schizophrenia, amyloidogenic disorders and
substance abuse.
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