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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Central Cardiovascular Control - Basic and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1983)
Loot Price: R2,908
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Central Cardiovascular Control - Basic and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1983)
Series: Current Topics in Neuroendocrinology, 3
Expected to ship within 10 - 15 working days
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The most prominent function of the central nervous system is the
control of motor functions by rapidly transmitted impulses through
efferent cranial and spinal peripheral nerves. Besides electrically
transmitted neural impulses, humoral mechanisms with more sustained
actions are exercised by the brain and spinal cord to regulate body
homeostasis. Thus, the brain may be regarded as an "endocrine
gland" discharging neurohormones (peptides) either into the general
circulation (neurohypophyseal hormones) or into the
hypothalamo-adenohypophyseal portal circulation (releasing and
inhibiting hormones). The brain, therefore, which is protected by
the blood-brain barrier from disturbing and potentially noxious
exogenous and endogenous agents circulating in the blood, has to
have certain neurohemal regions beyond this barrier, such as the
neural lobe and the median eminence (infundibulum), where neurohor
mones have free access to the blood stream. To regulate somatic and
autonomic functions in the best possible way, the central nervous
system is highly dependent on feedback signals conveyed through
somatic and visceral afferent nerves as well as on peripheral
humoral signals such as peripheral hormones and other circulating
substances that are under homeostatic regulation, e. g., peptides,
arnines, electrolytes, and other biologically active agents. In
this chapter, the role of the blood-brain barrier in the regulation
of these sub stances will be discussed with special emphasis on the
access through the blood-brain barrier to cardiovascular centers. 2
The Blood-Brain Barrier 2."
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