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cAMP Signaling - Methods and Protocols (Hardcover, 2015 ed.)
Loot Price: R3,641
Discovery Miles 36 410
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cAMP Signaling - Methods and Protocols (Hardcover, 2015 ed.)
Series: Methods in Molecular Biology, 1294
Expected to ship within 12 - 17 working days
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Total price: R3,661
Discovery Miles: 36 610
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This detailed volume encompasses new technological developments
that specifically address questions related to adenosine
3',5'-monophosphate (cAMP) compartmentalization, that probe
relevant protein-protein interactions, that increase the spatial
and temporal resolution of cAMP signal detection, and that can
facilitate integration of the mounting complexity of the
information that is becoming available on this signaling system.
cAMP, the prototypical intracellular second messenger, regulates a
large variety of cellular functions and biological processes,
including gene transcription, cell metabolism, proliferation,
development, as well as more specialized functions depending on the
cell type, so the realization of its extremely complex spatial
organization and local regulation is providing novel mechanistic
insight into cell physiology and is producing a novel framework for
the identification of disease mechanisms. Written in the highly
successful Methods in Molecular Biology series format, chapters
include introduction to their respective topics, lists of the
necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and tips on troubleshooting and
avoiding known pitfalls. Practical and authoritative, cAMP
Signaling: Methods and Protocols serves as a vital resource for
researchers working in this expanding, complex field.
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