Familial Mediterranean Fever (Hardcover, 2015 ed.)

This book, written by very well known opinion leaders in the field, covers all aspects of familial Mediterranean fever, the most common monogenic autoinflammatory disease. The opening chapters explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies. A large part of the book is then devoted to a detailed description of the typical and atypical clinical presentations, the disease course, and potential complications in both pediatric and adult patients. Guidance is provided on the measurement of disease severity and the management of patients in daily practice. The advice regarding treatment is based on the best currently available evidence and attention is also paid to important emerging treatments. The book is part of Springer's series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. Monogenic autoinflammatory diseases are hereditary disorders that are caused by single-gene defects in innate immune regulatory pathways and are characterized by a clinical and biological inflammatory syndrome in which there is limited, if any, evidence of autoimmunity. Familial Mediterranean fever itself is due to a mutation in the MEFV gene, which codes for the protein pyrin; it is characterized by periodic fever and episodes of painful inflammation in the abdomen, chest, and joints. Familial Mediterranean Fever will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with the disease.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Rare Diseases of the Immune System, 3
Release date:	March 2015
First published:	2015
Editors:	Marco Gattorno
Dimensions:	235 x 155 x 11mm (L x W x T)
Format:	Hardcover - Cloth over boards
Pages:	162
Edition:	2015 ed.
ISBN-13:	978-3-319-14614-0
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > Clinical & internal medicine > Rheumatology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	3-319-14614-9
Barcode:	9783319146140

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