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Familial Mediterranean Fever (Hardcover, 2015 ed.)
Loot Price: R3,269
Discovery Miles 32 690
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Familial Mediterranean Fever (Hardcover, 2015 ed.)
Series: Rare Diseases of the Immune System, 3
Expected to ship within 10 - 15 working days
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This book, written by very well known opinion leaders in the field,
covers all aspects of familial Mediterranean fever, the most common
monogenic autoinflammatory disease. The opening chapters explain
the genetic basis of the disease and provide insights into the
pathogenesis derived from recent experimental studies. A large part
of the book is then devoted to a detailed description of the
typical and atypical clinical presentations, the disease course,
and potential complications in both pediatric and adult patients.
Guidance is provided on the measurement of disease severity and the
management of patients in daily practice. The advice regarding
treatment is based on the best currently available evidence and
attention is also paid to important emerging treatments. The book
is part of Springer's series Rare Diseases of the Immune System,
which presents recently acquired knowledge on pathogenesis,
diagnosis, and therapy with the aim of promoting a more holistic
approach to these conditions. Monogenic autoinflammatory diseases
are hereditary disorders that are caused by single-gene defects in
innate immune regulatory pathways and are characterized by a
clinical and biological inflammatory syndrome in which there is
limited, if any, evidence of autoimmunity. Familial Mediterranean
fever itself is due to a mutation in the MEFV gene, which codes for
the protein pyrin; it is characterized by periodic fever and
episodes of painful inflammation in the abdomen, chest, and joints.
Familial Mediterranean Fever will be an invaluable source of
up-to-date information for all practitioners involved in the care
of patients with the disease.
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