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Books > Medicine > Clinical & internal medicine > Haematology
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Sickle Cell Disease - Genetics, Management & Prognosis (Hardcover)
Loot Price: R3,652
Discovery Miles 36 520
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Sickle Cell Disease - Genetics, Management & Prognosis (Hardcover)
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Sickle cell disease (SCD) is a genetic disorder caused by an
abnormality of hemoglobin. The disease is characterized by a
chronic hemolytic anemia. The search for affordable and accessible
medicines mainly from plants and having various modes of actions
for managing SCD is a priority in Africa where the disease is
endemic. The first chapter in this book reviews children with
Sickle Cell Disease (SCD). The authors also present their research
that shows that clinically, children with SCD behave differently
regarding their genetics. The second chapter gives an overview of
the current progress in research in calcium handling in red blood
cells of sickle cell disease patients, followed by an outlook into
the potential use of blockers of the cation channels for therapy of
SCD patients. The third chapter reviews and validates the
pharmacological relevance of "Gardenia ternifolia" and sustains the
use of this herbal medicine in the management of SCD in traditional
medical systems. The fourth chapter reviews the search and the
development of antisickling herbal drugs in Africa, where Sickle
cell disease (SCD) is an endemic. The last chapter reviews SCD and
its impact on sexual functioning as well as relationship dynamics.
Conclusions support the importance of social support and its
far-reaching impact into the coping mechanisms of patients with
chronic illness as well as quality of life.
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