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Breast Cancer: Scientific and Clinical Progress - Proceedings of the Biennial Conference for the International Association of Breast Cancer Research, Miami, Florida, USA - March 1-5, 1987 (Paperback, Softcover reprint of the original 1st ed. 1988)
Loot Price: R5,462
Discovery Miles 54 620
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Breast Cancer: Scientific and Clinical Progress - Proceedings of the Biennial Conference for the International Association of Breast Cancer Research, Miami, Florida, USA - March 1-5, 1987 (Paperback, Softcover reprint of the original 1st ed. 1988)
Series: Developments in Oncology, 56
Expected to ship within 10 - 15 working days
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Effective control of breast cancer depends on three types of
research accomplishment -- understanding the disease's origins and
progression: successfully applying this knowledge to methods of
detection, diagnosis and treatment: and finding ways to make these
advances truly available to the public as effectively as possible.
The significant progress that is occurring across this entire
spectrum of pioneering investigation is reflected in these
proceedings of the 1987 biennial conference of the International
Association for Breast Cancer Research. The first section of the
book focuses on oncogenes and chemical effectors that may play key
roles in early cell transformation leading to breast cancer.
Research discussed includes identification of specific oncogenes
which appear to be involved in the disease, study of their
activation and expression, examination of the biological effects of
various growth factors isolated from breast cancer cell lines, and
investigation of the molecular mechanisms by which estrogens
promote and stimulate growth of breast cancers. The second group of
chapters deals with several other complex factors and phenomena
which may influence tumor formation in the breast, for example,
expression of abnormalities by fibroblasts, disruption of
epithelial-mesenchymal interactions, and loss of ability nili to
synthesize normal basal lamina resulting in alterations in the
extracellular matrix. Clarification of the processes of normal
mammary gland development and differentiation is central to much of
this work.
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