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Pathogenesis of Idiopathic Scoliosis (Hardcover, 1st ed. 2018)
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Pathogenesis of Idiopathic Scoliosis (Hardcover, 1st ed. 2018)
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This book provides comprehensive coverage of current topics in
idiopathic scoliosis (IS). A three-dimensional deformity of the
spine, the condition is characterized by lateral curvature combined
with vertebral rotation. The primary lesion, however, lies in the
median sagittal plane, taking the form of a lordosis. Although the
clinical manifestations of scoliosis have been well documented, its
cause and pathogenesis have not yet been determined. Research into
what causes IS has focused on the structural elements of the spine,
spinal musculature, collagenous structures, the endocrine system,
the central nervous system, and genetics. Results of these studies
have brought about a new perception of IS epiphenomena, but the
main cause of IS remains unknown. Recently, several investigators
have produced new hypotheses regarding the cause of IS using the
developing techniques of genetics, biochemistry, and neurology.
This book is a review of the various causative factors thus far
proposed for IS and an introduction to the directions in which
research is heading to determine the primary cause of IS.
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