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Personalized Treatment of Breast Cancer (Hardcover, 1st ed. 2016)
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Personalized Treatment of Breast Cancer (Hardcover, 1st ed. 2016)
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This book deals with the essential factors in the personalization
of treatment for primary breast cancer. These include host issues,
lymph node surgery, radiation therapy, and preoperative systemic
treatment requiring specialized knowledge, multidisciplinary care
experience, techniques, and research. Locoregional treatment in
conjunction with systemic treatments is another important factor,
with options for local therapy significantly affected by genetic
BRCA mutation. Axillary treatment issues have become top priorities
in recent primary breast cancer care, and these are highlighted in
the book's presentation of technological advances in lymph node
mapping and diagnosis, axillary clearance in patients with nodal
metastasis, and the role of axillary surgery. Attention is also
given to locoregional treatment after preoperative systemic
therapy. Because therapeutic impact differs depending upon
biological characteristics such as tumor subtype, local therapy
should be based both on tumor biology and on therapeutic response
in parallel. Associated translational research and mathematical
prediction tools such as nomograms also are introduced. This book
provides the essence of primary breast cancer care, particularly
its individualization with novel therapeutic concepts and
strategies, and will greatly benefit physicians and clinical
investigators in breast cancer institutions.
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