QSAR studies on Topoisomerase-II inhibitors (Paperback)

The objective of drug discovery phase is to synthesize lead compounds, new analogs with improved potency, reduced off target activities, and physiochemical/metabolic properties suggestive of reasonable in vivo pharmacokinetics. This optimization is accomplished through empirical modification of the hit structure and/or by employing structure-based design if structural information about the target is available. The goal of present work is to design drug with minimum side effect and maximum potency. 2D QSAR is planned using Multiple Linear Regression Analysis, for achieving the goal, which can help in recognizing the important descriptor that can help in increasing the potency of anticancer drugs.

General

Imprint:	Lap Lambert Academic Publishing
Country of origin:	Germany
Release date:	June 2012
First published:	June 2012
Authors:	Meenakshi Sharma • Yashumati Ratan • Dharm Kishore
Dimensions:	229 x 152 x 6mm (L x W x T)
Format:	Paperback - Trade
Pages:	104
ISBN-13:	978-3-659-15980-0
Categories:	Books > Science & Mathematics > Chemistry > General
LSN:	3-659-15980-8
Barcode:	9783659159800

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!