Cancer is a devastating disease lacking an exact treatment. Recent
advances in genetics and biotechnology have provided a deeper
understanding of cancer biology, out of which aberrations in
oncogenes and tumour suppresser genes have arisen as important
etiological factors. Inactivation of tumour suppresser genes is one
of the initial cellular changes that ultimately lead to tumour
development. Thus, increasing knowledge about these genes aids in
the development of novel therapeutic applications as well as
identification of more effective and rapid molecular markers for
early diagnosis and prognostic evaluation. This book provides
up-to-date information on the structure, function and roles of the
main tumour suppresser genes thus far identified. An important
addition to the current literature in the field, this book is
intended to help instructors for teaching purposes and researchers
in the field of cancer biology as an overview of current knowledge.
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