The book will explain previously unconnected clinical data such as
why mammography works better for women age 50-59 than it does for
women age 40-49, why adjuvant chemotherapy works best for
premenopausal patients with positive lymph nodes, and it may also
explain the racial disparity in outcome. In particular, it points
to the perioperative period when systemic inflammation persists for
a week or so. This can lead to a variety of mechanisms whereby
single cancer cells (perhaps from the marrow) begin division and
angiogenesis of dormant avascular micrometastases occurs leading to
early relapses. With chapters presented from distinguished
scientists and physicians in a variety of specialties that relate
to and border the effects we present, this volume can be used as a
reference for practicing physicians and as a jumping-off point for
researchers to explore new therapeutic opportunities.
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