How Proteins Work is an up-to-date and authoritative account of
protein function in living systems, explained within the governing
parameters of physics, chemistry, and evolution. This text will
enable advanced undergraduate students in biochemistry and
biophysics to understand the relationships among protein function,
structure, and dynamics. It will also serve as a valuable resource
for graduate students and researchers looking for a reference on
the fundamentals underlying protein function. By providing an
integrated view of proteins at both a cellular and systemic level,
this textbook shows how evolution drives proteins to adopt domain
structures that combine to achieve biological outcomes. The
association of proteins into dimers, molecular machines, and
multi-enzymatic complexes enables them to achieve catalytic and
functional efficiency.
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