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Glycans in Cell Interaction and Recognition (Hardcover)
Loot Price: R4,303
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Glycans in Cell Interaction and Recognition (Hardcover)
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The modulation of cellular interactions represents a crucial aspect of many inter and intra-cellular processes, including the regulation of gene expression, cell growth, migration, differentiation and apoptosis. Glycoproteins, which constitutes one of the major groups of adhesion molecules and receptors, plays an important role in such processes and over the last decade, research has highlighted the therapeutic implications this has for many physiological and pathological processes such as inflammation, arthritis and metastasis.;The first part of this book deals with the structure and biosynthesis of glycoconjugates, in addition to reviewing the structure and metabolism of glycosaminoglycans and glycolipids. It also features a general overview of cellular adhesion mechanisms and the extra-cellular matrix.;The second part addresses the pathological roles played by glycoconjugates and their potential therapeutic applications, for example in the progression of cancer, neurophysiopathologies and carbohydrate deficient glycoprotein syndromes.
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