Inflammatory Disorders (Hardcover, 2015 ed.)

The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Neuroscience and Respiration, 839
Release date:	November 2014
First published:	2015
Editors:	Mieczyslaw Pokorski
Dimensions:	254 x 178 x 6mm (L x W x T)
Format:	Hardcover
Pages:	67
Edition:	2015 ed.
ISBN-13:	978-3-319-10011-1
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > General Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	3-319-10011-4
Barcode:	9783319100111

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