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Adenovirus - Methods and Protocols (Hardcover, 3rd ed. 2014)
Loot Price: R4,140
Discovery Miles 41 400
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Adenovirus - Methods and Protocols (Hardcover, 3rd ed. 2014)
Series: Methods in Molecular Biology, 1089
Expected to ship within 10 - 15 working days
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Reflecting the development of powerful new tools and
high-throughput methods to analyze adenoviral particles and their
interactions with host cells, the third edition of Adenovirus
Methods and Protocols calls upon experts in the field to convey
advances in molecular biology, genomics and proteomics, imaging,
and bioinformatics. Beginning with cryo-electron microscopy, atomic
force microscopy, and mass spectrometry for a high resolution image
and characterization of the virion, this detailed book then
continues with capsid modifications and viral-like particles as
promising alternatives to classical adenovirus vectors, and the
study of adenovirus in host interactions in vitro at the cellular
level as well as in vivo in animal models. Finally, the volume
concludes with an extensive update of the most efficient protocols
to generate, amplify, and/or purify, at small and large scale,
standard human Ad5 as well as non-human, chimeric, and
helper-dependent adenovirus vectors. Written in the greatly
successful Methods in Molecular Biology series format, chapters
include introductions to their respective topics, lists of the
necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and tips on troubleshooting and
avoiding known pitfalls. Comprehensive and cutting-edge, Adenovirus
Methods and Protocols, Third Edition serves as an ideal guide for
scientists continuing to research this highly valuable viral tool.
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