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Pulmonary Immunotoxicology (Hardcover, 2000 ed.)
Loot Price: R4,860
Discovery Miles 48 600
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Pulmonary Immunotoxicology (Hardcover, 2000 ed.)
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Pulmonary Immunotoxicology is a comprehensive exploration of the
effects of various inhaled materials upon the immune system of the
respiratory tract. It will be useful to investigators in the field
of pulmonary toxicology and immunotoxicology, and to those involved
in administration and regulation of matters related to inhaled
materials. It can also serve as a textbook for a course in
pulmonary immunotoxicology at graduate or advanced undergraduate
level. Pulmonary Immunotoxicology comprises four sections. The
first provides basic background concepts essential for
understanding pulmonary immunotoxicology, including discussions of
the normal structure and function of the respiratory system, its
basic immunology, and the manner by which inhaled particles and
gases are removed from the air and deposited upon respiratory tract
surfaces. The second section provides an overview of the major
types of pathological consequences which can arise from
immunomodulation within the respiratory tract, including
hypersensitivity and asthma, inflammation and fibrosis, as well as
immunosuppression and autoimmunity. The third section, which
comprises the largest portion of the book, deals specifically with
major classes of airborne agents that are known to alter the immune
function of the respiratory tract. These are arranged into major
classes: organic agents, metals, gases, particles, biologics, and
complex mixtures. The fourth and final section of the book explores
the area of risk assessment, including discussions of the basic
concepts of risk assessment as they apply specifically to
immunotoxicologic effects upon the lungs, and the use of biomarkers
as indices of potential pulmonary immunotoxic responses to inhaled
materials.
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