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Cellular Mechanotransduction - Diverse Perspectives from Molecules to Tissues (Hardcover, New)
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Cellular Mechanotransduction - Diverse Perspectives from Molecules to Tissues (Hardcover, New)
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'Mechanotransduction' is the term for the ability, first described
by 19th-century anatomist Julius Wolff, of living tissues to sense
mechanical stress and respond by tissue remodeling. More recently,
the scope of mechanotransduction has been expanded to include the
sensation of stress, its translation into a biochemical signal, and
the sequence of biological responses it produces. This book looks
at mechanotransduction in a more restricted sense, focusing on the
process of stress sensing and transducing a mechanical force into a
cascade of biochemical signals. This stress has become increasingly
recognized as one of the primary and essential factors controlling
biological functions, ultimately affecting the function of the
cells, tissues, and organs. A primary goal of this broad book is
also to help define the new field of mechanomics, which attempts to
describe the complete mechanical state of a biological system.
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