Dr. Myrtle A. Davis has assembled a panel of cutting-edge
scientists to describe their best methods for detecting,
illuminating, and quantifying apoptotic mechanisms in a way that is
useful for the design of toxicology and pharmacology studies. These
state-of-the-art techniques include flow cytometric, fluorometric,
and laser scanning methods for quantifying and characterizing
apoptosis, as well as protocols for the use of DNA microarray
technology, high throughput screens, and ELISA. Immunocytochemical
methods for measuring biochemical and molecular endpoints in tissue
sections will be highly useful for those carrying out studies in
whole animal models as opposed to cell culture systems.
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