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Advances in Echo Imaging Using Contrast Enhancement (Paperback, Softcover reprint of the original 1st ed. 1993)
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Advances in Echo Imaging Using Contrast Enhancement (Paperback, Softcover reprint of the original 1st ed. 1993)
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The opacification of the left ventricle by echo cardiographic
contrast agents (echoventriculography) represents an alternative to
cineventriculography, as determinations of left ventricular volume
and ejection fraction are accurate and highly reproducible, when
methods like color superposition and statist- ical imaging
techniques are used in order to improve the outlining of the cavity
and endocardial border. Detection of perfusion defects is possible
[40]. The enhancement of myocardial contrast during the perfusion
phase after injection into the left ventricle or the aorta further
improves the endo- cardial border delineation. For practical
purposes, the direct injection of echocardiographic contrast is
inferior to the indirect opacification after per- ipheral venous
injection which can be achieved with sonicated albumin, Albunex(R),
SH U 508 A, HOE 155. These drugs are presently under clinical
investigation. In up to 90% of the patients, left heart
opacification is possible, yielding 30% intensity of the right
ventricle. When these drugs are available, sophisticated computed
methodologies have to be included in the echocardio- graphic
machines in order to improve the determination of the left
ventricular volume and ejection fraction [44]. In the future,
cineventriculography will be rarely performed as
echoventriculograms already show left ventricular contraction. This
will possibly result in reduced side effects and costs. REFERENCES
1. Gramiak R, Shah PM, Kramer DH. Ultrasound cardiography: Contrast
studies in anatomy and function. Radiology 1969; 939. 2. Kronik G,
Hutterer B, Mosslacher H. Diagnose atrialer Links-rechts-Shunts mit
Hilfe der zweidimensionalen Kontrastechokardiographie. Z Kardiol
1981;70:138-45.
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