The book reviews the main approaches for generation of
differentiated cells from various types of stem cells, including
embryonic, placental and cord blood stem cells through marrow,
adipose tissue and dental pulp. The book starts with an overview of
experimental protocols applied to generate insulin secreting cells,
neural cells, heart cells, and other tissue specific cells ex vivo
and in experimental animals. This is followed by exhaustive review
of clinical trials in these pathologies. It continues with a
comparison of the merits of successful transplantation in humans
versus animal experimentation, and highlights the most promising
clinical applications in the field. Special chapters are devoted to
the topic of tissue engineering and modern synthetic and biological
scaffolds. It is essential reading for scientists and researchers
in tissue engineering and stem cell research as well as clinicians
who are involved in developing or testing stem cell therapies.
General
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