Advancing Progress in the Development of Combination Cancer Therapies with Immune Checkpoint Inhibitors - Proceedings of a Workshop (Paperback)

In recent years, significant progress has been made in the clinical development and use of various types of cancer immunotherapy, all of which rely on the immune system to fight cancer. The majority of new cancer drug applications submitted to the Food and Drug Administration (FDA) are for immunotherapies or combinations involving immunotherapies. One type of immunotherapy is an immune checkpoint inhibitor. Cells in the human body have proteins that regulate the immune system response to foreign invaders (e.g., cancer cells, microorganisms). However, cancer cells can coopt these "checkpoint" proteins and thwart the immune system's ability to recognize and attack cancer cells. To help promote an immune response to cancer, researchers have developed immune checkpoint inhibitors that enable T-cells to recognize cancer cells as foreign and to prevent deactivation of an immune system response. To examine the challenges and opportunities to develop combination cancer therapies that include immune checkpoint inhibitors, the National Cancer Policy Forum held a workshop on July 16?17, 2018, in Washington, DC. This workshop convened stakeholders with a broad range of expertise, including cancer researchers, clinicians, patient advocates, and representatives from industry, academia, and government. This publication summarizes the presentations and discussions from the workshop. Table of Contents Front Matter Proceedings of a Workshop Appendix A: Statement of Task Appendix B: Workshop Agenda

General

Imprint:	National Academies Press
Country of origin:	United States
Release date:	October 2019
First published:	2019
Authors:	National Academies of Sciences, Engineering, and Medicine • Health and Medicine Division • Board on Health Care Services • National Cancer Policy Forum
Editors:	Sharyl J. Nass • Erin Balogh
Dimensions:	229 x 152mm (L x W)
Format:	Paperback
Pages:	88
ISBN-13:	978-0-309-49086-3
Categories:	Books > Medicine > General issues > Health systems & services > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	0-309-49086-3
Barcode:	9780309490863

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