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Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research - Proceedings of a Workshop (Paperback)
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Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research - Proceedings of a Workshop (Paperback)
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The marmoset, a type of small monkey native to South America, is a
research model of increasing importance for biomedical research in
the United States and globally. Marmosets offer a range of
advantages as animal models in neuroscience, aging, infectious
diseases, and other fields of study. They may be particularly
useful for the development of new disease models using genetic
engineering and assisted reproductive technologies. However,
concerns have been voiced with respect to the development of new
marmoset-based models of disease, ethical considerations for their
use, the supply of marmosets available for research, and gaps in
guidance for their care and management. To explore and address
these concerns, the Roundtable on Science and Welfare in Laboratory
Animal Use hosted a public workshop on October 22-23, 2018, in
Washington, DC. The workshop focused on the availability of
marmosets in the United States and abroad; animal welfare and
ethical considerations stemming from the use of wildtype and
genetically modified marmosets; and standards of housing and care,
dietary needs, and feeding requirements for marmosets in captivity.
This publication summarizes the presentations and discussions from
the workshop. Table of Contents Front Matter 1 Introduction 2
Context for the Use of Marmosets as Animal Models 3 Ethical
Considerations 4 Current Research Applications 5 Marmoset Genomics
and Genetic Diversity 6 Marmoset Supply and Availability 7 Marmoset
Care and Management 8 Final Remarks Appendix A: Workshop Agenda
Appendix B: Professional Biosketches
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