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Exploring Psychedelics and Entactogens as Treatments for Psychiatric Disorders - Proceedings of a Workshop (Paperback)
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Exploring Psychedelics and Entactogens as Treatments for Psychiatric Disorders - Proceedings of a Workshop (Paperback)
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Loot Price R478
Discovery Miles 4 780
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Psychiatric illnesses - such as major depressive disorder, anxiety
disorder, substance use disorder, and posttraumatic stress disorder
(PTSD) - are widely prevalent and represent a substantial health
burden worldwide. Yet, conventional medications for mental
illnesses often fail to provide relief to patients' disruptive and
disabling symptoms. Existing and emerging evidence that
psychedelics (e.g., LSD and psilocybin) and entactogens (e.g.,
MDMA) may be useful as tools to alleviate mental illness has
sparked a renaissance of interest by investigators, clinicians,
drug developers, and patient advocates in recent years. While
promising data on therapeutic efficacy has energized research and
development, resolving the mechanisms of action will be important
for optimizing the efficacy and safety of these medicines. Further,
evaluating the effect of psychedelics and entactogens on mood and
behavior comes with unique challenges still in need of resolution.
These include unresolved questions relating to blinding, placebo
and nocebo effects, and the impact of psychosocial contexts. In
response to this renewed interest, the National Academies of
Sciences, Engineering, and Medicine's Forum on Neuroscience and
Nervous System Disorders convened a workshop on March 29-30, 2022.
The workshop brought together a diverse group of stakeholders to
explore the use of psychedelics and entactogens as treatments for
psychiatric disorders. This Proceedings of a Workshop summarizes
the presentations and discussions of the workshop. Table of
Contents Front Matter 1 Introduction and Background 2 History and
Current Status of Psychedelics and Entactogens for the Treatment of
Psychiatric Disorders 3 Mechanisms of Action and Key Research Gaps
for Psychedelics and Entactogens 4 Advancing Clinical Development:
Challenges and Opportunities 5 Anticipating Implementation to Guide
Clinical Research and Development 6 Reflecting on the Road Ahead
Appendix A: References Appendix B: Workshop Agenda
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