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Advanced Cancer - Managing Symptoms & Quality of Life (Hardcover)
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Advanced Cancer - Managing Symptoms & Quality of Life (Hardcover)
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Bone metastases are a common event for cancer patients. We have
developed an innovative and unique clinical research program
dedicated to palliative radiation oncology at the Odette Cancer
Centre, Sunnybrook Health Sciences Centre and specifically a
multidisciplinary clinic for bone metastases. The development of
this program introduces an effective strategy to conduct research
in palliative radiation oncology. Symptom control is very important
for the quality of life for bone and brain metastases patients.
This is an evolving active field of research as greater emphasis is
being placed into understanding the goals of improving not only a
patient's survival, but the ability for therapies to improve the
quality of a patient's life. In this book we present the EORTC
QLQ-C30 questionnaire, which was used in a multi-center study with
patients recruited from Edmonton, Alberta, Canada; Kaohsiung,
Taiwan; Kerala, India; Nicosia, Cyprus; Sao Paulo, Brazil; Taipei,
Taiwan; Tanta, Egypt; and Toronto, Ontario, Canada, with brain and
bone metastases. It was found that the difficulties bone and brain
metastases patients experience are different in several ways.
Patients with bone metastases have more pain and reduced physical
functioning. However, patients with brain metastases have more
severe role functioning deficits. With use of the QLQ-C30, it was
also found that there is ambiguity regarding the root of patient
issues. Future studies that require more comprehensive
disease-specific findings should include disease-specific
assessment modules such as the QLQ-BM22 and QLQ-BN20. Important
domains such as the minimal clinically important difference should
also be established in individual subgroups of patients to assist
in clinical trial design.
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