In Targets for Cancer Chemotherapy: Transcription Factors and Other
Nuclear Proteins, a panel of leading basic researchers,
pharmaceutical scientists, and clinical oncologists explain in
detail the therapeutically-relevant protein targets that contribute
to cancer pathology and spell out their implications for cancer
drug discovery and clinical application. The authors identify and
illuminate selected transcription factor oncoproteins and tumor
suppressors, together with nuclear proteins that are central to the
phenotype of the tumor cell involved in chromatin control. The
emphasis is on new targets and approaches to cancer treatment
derived from the cancer cell cycle, gene control targets, and
angiogenesis.
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