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Books > Medicine > Clinical & internal medicine > Paediatric medicine
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The Neurology of Neuroblastoma - Neuroblastoma as a Neurobiological Disease (Hardcover, 2002 ed.)
Loot Price: R2,928
Discovery Miles 29 280
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The Neurology of Neuroblastoma - Neuroblastoma as a Neurobiological Disease (Hardcover, 2002 ed.)
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Neuroblastoma is the single most common solid tumor of childhood.
Although children with small primary neuroblastomas alone are
almost always cured by surgery, 65% of children with neuroblastoma
already have large bulky tumors or metastatic disease by the time
of initial diagnosis. For these children, the 5-year survival rate
is only somewhere between 5% and 20% with therapies including
surgery, radiation, chemotherapy, and bone marrow transplantation.
Dr Schor outlines a new approach to these tumors in order to make a
difference for these children. There is much information to support
the notion that neuroblastomas represent a developmental aberration
of the nervous system, rather than a de novo abnormality in a
previously normal cell. While the remote, paraneoplastic effects of
neuroblastoma are often the purview of the child neurologist, the
neoplasm itself has been viewed and approached therapeutically in
much the same manner as all other solid tumors, as the purview of
the pediatric oncologist. This work takes the view that approaching
neuroblastoma rather as a disorder of nervous system development
offers new therapeutic possibilities for this common tumor of
childhood.
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