Cross-Coupling Reactions - A Practical Guide (Paperback, Softcover reprint of the original 1st ed. 2002)

In 1972, a very powerful catalytic cycle for carbon-carbon bond formation was 2 first discovered by the coupling reaction of Grignard reagents at the sp -carbon. Over the past 30 years, the protocol has been substantially improved and expanded to other coupling reactions of Li, B, N, O, Al, Si, P, S, Cu, Mn, Zn, In, Sn, and Hg compounds. These reactions provided an indispensable and simple methodology for preparative organic chemists. Due to the simplicity and rel- bility in the carbon-carbon, carbon-heteroatom, and carbon-metalloid bo- formations, as well as high efficiency of the catalytic process, the reactions have been widely employed by organic chemists in various fields. Application of the protocol ranges from various syntheses of complex natural products to the preparation of biologically relevant molecules including drugs, and of sup- molecules, and to functional materials. The reactions on solid surfaces allow robot synthesis and combinatorial synthesis. Now, many organic chemists do not hesitate to use transition metal complexes for the transformation of org- ic molecules. Indeed, innumerable organic syntheses have been realized by the catalyzed reactions of transition metal complexes that are not achievable by t- ditional synthetic methods. Among these, the metal-catalyzed cross-coupling reactions have undoubtedly contributed greatly to the development of such a new area of "metal-catalyzed organic syntheses." An excellent monograph for the cross-coupling reactions and other met- catalyzed C-C bond-forming reactions recently appeared in Metal-catalyzed Cross-coupling Reactions (Wiley-VCH,19

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Topics in Current Chemistry, 219
Release date:	December 2010
First published:	2002
Editors:	Norio Miyaura
Contributors:	S. L. Buchwald • K. Fugami • T. Hiyama • M. Kosugi • M. Miura • N. Miyaura • A.R. Muci • M. Nomura • E. Shirakawa
Dimensions:	235 x 155 x 16mm (L x W x T)
Format:	Paperback
Pages:	248
Edition:	Softcover reprint of the original 1st ed. 2002
ISBN-13:	978-3-642-07576-6
Categories:	Books > Science & Mathematics > Chemistry > Inorganic chemistry > General Books > Science & Mathematics > Chemistry > Organic chemistry > General Books > Science & Mathematics > Chemistry > Physical chemistry > General
LSN:	3-642-07576-2
Barcode:	9783642075766

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