Algorithms and Methods in Structural Bioinformatics (Hardcover, 1st ed. 2022)

The three-dimensional structure and function of molecules present many challenges and opportunities for developing an understanding of biological systems. With the increasing availability of molecular structures and the advancing accuracy of structure predictions and molecular simulations, the space for algorithmic advancement on many analytical and predictive problems is both broad and deep. To support this field, a rich set of methods and algorithms are available, addressing a variety of important problems such as protein-protein interactions, the effect of mutations on protein structure and function, and protein structure determination. Despite recent advancements in the field, in particular in protein folding with the development of AlphaFold, many problems still remain unsolved. In this book we focus on a number of topics in Structural Bioinformatics: Cryo-EM structural detection, protein conformational exploration, elucidation of molecular binding surface using geometry, the effect of mutations, insertions and deletions on protein structural stability, and protein-ligand binding.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Computational Biology
Release date:	September 2022
First published:	2022
Editors:	Nurit Haspel • Filip Jagodzinski • Kevin Molloy
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	114
Edition:	1st ed. 2022
ISBN-13:	978-3-03-105913-1
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Computing & IT > Social & legal aspects of computing > Health & safety aspects of computing Promotions
LSN:	3-03-105913-1
Barcode:	9783031059131

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