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The Notochord - Development, Evolution and contributions to the vertebral column (Hardcover)
Loot Price: R3,270
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The Notochord - Development, Evolution and contributions to the vertebral column (Hardcover)
Series: Evolutionary Cell Biology
Expected to ship within 12 - 17 working days
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Although it is the defining organ of the Chordata, the notochord
and its cells are one of the least understood vertebrate organs.
This may be because large parts of the notochord are often replaced
with cartilaginous or bony vertebral bodies. The presence of
cartilage in the notochord raises questions about the evolutionary
relationships between notochord cells and cartilage cells. This
book integrates classical analytical studies with recent
palaeontological, experimental, and molecular studies in both
developmental and evolutionary contexts. For example, although the
early signaling function of the notochord is conserved across the
vertebrates, many will be surprised to find that the role of the
notochord in vertebral body development in tetrapods is not the
blueprint for all vertebrates. Recent studies on zebrafish and
medaka embryos have uncovered the molecular mechanisms of a
somite-independent notochord-driven segmentation process that
establishes vertebral centra and intervertebral spaces. As this
process is not restricted to teleosts, the authors have written a
general discussion about the role of the notochord in vertebral
formation. Modularity and segmentation of the vertebral column are
related topics. Further overarching themes are the structure,
function and fate of the notochord in adult vertebrates and
notochord-cartilage relationships. Key Features The first book
devoted to notochord development, function and evolution Includes
and integrates information on the notochord from studies going back
169 years Integrates developmental, molecular, functional,
experimental and palaeontological studies Documents the fate of the
notochord across the vertebrates Extensively illustrated with
classical and new images Related Titles Bard, J. Evolution: The
Origins and Mechanisms of Diversity (ISNB 978-0-3673-5701-6) Leys,
S. and Hejnol. A. Origin and Evolution of Metazoan Cell Types (ISBN
978-1-1380-3269-9)
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