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Advances in Research on Neurodegeneration - Volume 5 (Paperback, Softcover reprint of the original 1st ed. 1997)
Loot Price: R1,503
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Advances in Research on Neurodegeneration - Volume 5 (Paperback, Softcover reprint of the original 1st ed. 1997)
Series: Journal of Neural Transmission. Supplementa, 50
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Volume 5 of the series "Advances in Research on Neurodegeneration"
is concerned with themes which are currently the focus of intensive
research, and in which advances in our understanding of the
pathological mechanisms un derlying neurodegenerative diseases are
expected in the near future. The first section contains five
reviews devoted to the various neuroimaging technolo gies. The
discussion is concerned with the question of whether neuroimaging
techniques make it possible to follow the process of degeneration
as it occurs, and which methods offer the required sensitivity and
quantifiability for this purpose. However, the question needs to be
examined of whether, given the physical and chemical limitations of
these techniques, even under optimal conditions, anatomical
resolution can be improved to the extent that neuro degenerative
diseases can be diagnosed earlier than currently possible and a
confident diagnosis made. The possibilities of using neuroimaging
techniques to provide information regarding the effects of
neuroprotective or neuroregen erative therapeutic strategies, and
for correlating the results of neuropsycho logical research with
imaging data are also discussed. The second section is concerned
with the significance of endogenous or exogenous neurotoxins as
triggers for neurodegenerative processes that may lead to
Parkinsonism. Vulnerability factors, which include such factors as
nerve ending sensitivity, the synergistic effects of drugs and the
various mechanisms underlying different toxins are discussed."
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