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Protein-Protein Interactions (Hardcover, New)
Loot Price: R4,709
Discovery Miles 47 090
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Protein-Protein Interactions (Hardcover, New)
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This book describes the fundamental physical, chemical, molecular
and biological aspects of proteins binding to one another in
cellular biology. PPI is a common phenomenon in cell and molecular
biology events. The networks of PPI describe cellular function in
both unicellular and multi-cellular organisms. Homo complexes
(dimers of identical monomers) or hetero complexes (dimers of
non-identical monomers) are involved in PPI. These complexes are
common in catalysis, regulation and structural assembly. However,
the molecular principles of protein interactions are difficult to
understand due to the geometrical and chemical characteristics of
proteins. The challenge today is to identify interaction partners
and sites from sequence and/or structures. This book describes the
principles (physics and chemistry) of PPI and protein interfaces to
develop models for PPI predictions.
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