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Peritoneal Carcinomatosis: Principles of Management (Hardcover, 1996 ed.)
Loot Price: R8,202
Discovery Miles 82 020
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Peritoneal Carcinomatosis: Principles of Management (Hardcover, 1996 ed.)
Series: Cancer Treatment and Research, 82
Expected to ship within 12 - 17 working days
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Paul Sugarbaker and his colleagues have persevered in the study and
treat ment of peritoneal carcinomatosis. The peritoneal cavity has
many unique and incompletely appreciated properties. These
properties, coupled with the biologic behavior of many cancers,
results in the seeding and growth of these cancers on the
peritoneum. Many of these cancers remain localized to the
peritoneum only, never metastasizing to other sites. One possible
reason for this may be the obstruction of the afferent lymphatics
on the undersurface of the diaphragm. The mucopolysaccharides
produced by many of these neoplasma are probably viscous enough to
obstruct these lymphatics, leading to the syndrome of pseudomyxoma
peritonei. Many of the neoplasms taking residence on the peritoneum
have extremely long cell-cycle times and are resistant to
radiotherapy and many chemotherapeutic agents. How ever, much can
be done for these patients - resection of primary cancers,
omentectomies to reduce ascites formation, management of recurrent
ascites, management of intestinal obstruction, nutritional care,
and, hopefully, intraperitoneal chemotherapy. We have reviewed many
of these problems in the past [1-7]. Dr. Sugarbaker and his
colleagues have organized the current state of knowledge and
technology for continuing use. The book provides a basis for
thoughtful, prospective research planning. John S. Spratt, M. D. ,
F. A. C. S. Professor of Surgery The James Graham Brown Cancer
Center University of Louisville Louisville, Kentucky References 1.
Long RTL, Spratt JS, Dowling E.
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