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Prognostic Factors in Cancer (Paperback, illustrated edition)
Loot Price: R2,863
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Prognostic Factors in Cancer (Paperback, illustrated edition)
Series: UICC International Union Against Cancer
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M. K. Gospodarowicz, P. Hermanek, and D. E. Henson Attention to
innovations in cancer treatment has tended to eclipse the
importance of prognostic assessment. However, the recognition that
prognostic factors often have a greater impact on outcome than
available therapies and the proliferation of biochemical,
molecular, and genetic markers have resulted in renewed interest in
this field. The outcome in patients with cancer is determined by a
combination of numerous factors. Presently, the most widely
recognized are the extent of disease, histologic type of tumor, and
treatment. It has been known for some time that additional factors
also influence outcome. These include histologic grade, lymphatic
or vascular invasion, mitotic index, performance status, symptoms,
and most recently genetic and biochemical markers. It is the aim of
this volume to compile those prognostic factors that have emerged
as important determinants of outcome for tumors at various sites.
This compilation represents the first phase of a more extensive
process to integrate all prognostic factors in cancer to further
enhance the prediction of outcome following treatment. Certain
issues surround ing the assessment and reporting of prognostic
factors are also considered. Importance of Prognostic Factors
Prognostic factors in cancer often have an immense influence on
outcome, while treatment often has a much weaker effect. For
example, the influence of the presence of lymph node involvement on
survival of patients with metastatic breast cancer is much greater
than the effect of adjuvant treatment with tamoxifen in the same
group of patients 5]."
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