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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Voltage Gated Sodium Channels (Paperback, Softcover reprint of the original 1st ed. 2014)
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Voltage Gated Sodium Channels (Paperback, Softcover reprint of the original 1st ed. 2014)
Series: Handbook of Experimental Pharmacology, 221
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A number of techniques to study ion channels have been developed
since the electrical basis of excitability was first discovered.
Ion channel biophysicists have at their disposal a rich and
ever-growing array of instruments and reagents to explore the
biophysical and structural basis of sodium channel behavior. Armed
with these tools, researchers have made increasingly dramatic
discoveries about sodium channels, culminating most recently in
crystal structures of voltage-gated sodium channels from bacteria.
These structures, along with those from other channels, give
unprecedented insight into the structural basis of sodium channel
function. This volume of the Handbook of Experimental Pharmacology
will explore sodium channels from the perspectives of their
biophysical behavior, their structure, the drugs and toxins with
which they are known to interact, acquired and inherited diseases
that affect sodium channels and the techniques with which their
biophysical and structural properties are studied.
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