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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Phospholipid Metabolism in Apoptosis (Hardcover, 2002 ed.)
Loot Price: R4,553
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Phospholipid Metabolism in Apoptosis (Hardcover, 2002 ed.)
Series: Subcellular Biochemistry, 36
Expected to ship within 10 - 15 working days
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The last few years have witnessed an explosion of both interest and
knowledge about apoptosis, the process by which a cell actively
commits suicide. The number of publications on the topic has
increased from nothing in the early 1980s to more than 10,000
papers annually today. It is now well recognized that apoptosis is
essential in many aspects of normal development and is required for
maintaining tissue homeostasis. The idea that life requires death
seems somewhat paradoxical, but cell suicide is essential for an
animal to survive. For example, without selective destruction of
"non-self" T cells, an animal would lack immunity. Similarly,
meaningful neural connections in the brain are whittled from a mass
of cells. Further, developmental cell remodeling during tissue
maturation involves programmed cell death as the major mechanism
for functional and structural safe transition of undifferentiated
cells to more specialized counterparts. Apoptosis research, with
roots in biochemistry, developmental and cell biology, genetics,
and immunology, embraces this long-ignored natural law. Failure to
properly regulate apoptosis can have catastrophic consequences.
Cancer and many diseases (AIDS, Alzheimer's disease, Parkinson's
disease, heart attack, stroke, etc. ) are thought to arise from
deregulation of apoptosis. As apoptosis emerges as a key biological
regulatory mechanism, it has become harder and harder to keep up
with new developments in this field.
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